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Clinical Manifestations of Late-Onset Hypogonadism and Their Anticipated Response to Treatment
|
Body Function |
Effect of Aging |
Response to Testosterone |
|
penile erections |
worse |
better |
|
sexual desire (libido) |
worse |
better |
|
mood and thought clarity |
no change or worse |
better |
|
tiredness (fatigue) |
worse |
better |
|
sleep disturbance |
no change or worse |
no change |
|
spacial cognition |
worse |
possibly better |
|
hot flashes |
worse |
better |
|
quality of life |
worse |
better |
|
hemoglobin & hematocrit (blood count) |
decrease |
increase |
|
leptin production |
increase |
decrease |
|
LDL and HDL cholesterol |
no change |
decrease |
|
fat mass |
increase |
decrease |
|
muscle mass |
decrease |
increase |
|
bone mass |
decrease |
increase |
|
hair and skin changes |
worse |
no change |
|
(Source: Alvaro Morales, Androgen Deficiency in the Aging Male, Campbell-Walsh Urology, Table 29-1, Clinical Manifestations of Late-Onset Hypogonadism and Their Anticipated Response to Treatment) |